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Helios XT

PHARMACEUTICAL GRADE FAT BURNER

Let’s face it, muscle underneath fat looks like fat. To have a truly godlike physique, it takes more than herculean muscle. Helios XT maximizes thermogenesis, reliance on fat as fuel, appetite suppression, and hormone regulation to make your physique look as though it were carved from stone. You see, fat loss isn’t a matter of on or off. Numerous organ systems must work with synergy to create tangible body fat reduction. Helios XT does just that – every ingredient works together for one goal, ripped physiques. Look like the gods themselves with Helios XT.

$59.99

Product ID: 1620 Category: .

helioslabel

There is nothing really quite as epic as the Greek gods. The stories about them exemplify this so much that they can’t even be called stories at all, rather they must be called epics. In Greek mythology, Helios is the Titan god of the sun, known for his good looks, muscular build, and obviously, the burning hot sun. So when DNA Pharma’s research and development team put together our Pharmaceutical Grade Fat Burner, we knew the perfect name for it already – Helios XT. Because nothing can burn fat like the sun. Let’s take a look inside the capsule and see exactly what composes a supreme fat burning formula:

Caffeine Anhydrous – The single most substantiated metabolism-boosting ingredient. Increases calorie-burn, fat oxidation, and satiety.

Theacrine – Offers psychomotor benefit, reducing fatigue and increasing alertness.

N-phenethyldimethylamine HCL – Structurally similar to DMAA and believed to create sensations of euphoria while potentially augmenting fat loss.

Higenamine – A beta-2 adrenergic stimulant and similar in composition to ephedrine, this ingredient interacts with the adrenal glands to induce weight loss.

Cayenne Pepper Extract – Several contents of hot peppers are alkaloids that induce fat-burning effects within the body.

Ginger Extract – Ginger is a jack of all trades – capable of increasing the thermic effect of food and supporting healthy sex hormone profiles in addition to a wide array of other health benefits.

Yohimbine HCL – Boosts the body’s potential to burn fat and increase blood flow.

CapsiAtra™ Dihydrocapsiate – A capsaicinoid that works to increase thermogenesis and shift metabolism to rely on fatty acids instead of glucose.

Let’s face it, muscle underneath fat looks like fat. To have a truly godlike physique, it takes more than herculean muscle. Helios XT maximizes thermogenesis, reliance on fat as fuel, appetite suppression, and hormone regulation to make your physique look as though it were carved from stone. You see, fat loss isn’t a matter of on or off. Numerous organ systems must work with synergy to create tangible body fat reduction. Helios XT does just that – every ingredient works together for one goal, ripped physiques. Look like the gods themselves with Helios XT.

Niacin:

Niacin is a form of Vitamin B3. Vitamin B3 is found in many foods including yeast, meat, fish, milk, eggs, green vegetables, beans, and cereal grains.

  • Niacin promotes health in the nervous system, digestive system, skin, hair and eyes.
  • Niacin has long been used to increase high-density lipoprotein (HDL), or the “good,” cholesterol. HDL cholesterol helps sweep up low-density lipoprotein (LDL), or the “bad,” cholesterol, in your bloodstream.
  • Niacin also helps improve liver function, metabolize food, and helps your adrenal glands produce sex and stress hormones.
  • Niacin is also known for increasing blood circulation.
  • Blond et al. discovered in 20 men without diabetes but with dyslipidemia, 2g niacin supplementation over the course of eight weeks promoted a reduction in triglycerides (28%) and vLDL (68%) while increasing HDL cholesterol (17%).

Vitamin B6:

B6 is a water soluble vitamin that is important to various metabolic reactions that occur in the body. It is also a coenzyme for protein metabolism and nervous and immune system function. Furthermore, it is involved in the synthesis of hormones and red blood cells.

  • B6 helps to protect the heart from cholesterol deposits and helps to prevent kidney stone formation.
  • B6 also helps activate coenzymes that are important in metabolism.

Magnesium:

Magnesium is an essential mineral and electrolyte. It is involved in protein synthesis, ATP formation, metabolism of carbohydrates and fats, and bone strength.

  • Magnesium deficiencies are the second most common deficiency in developed countries. A lack of magnesium will raise blood pressure and reduce insulin sensitivity.
  • Increases in free and total testosterone have been noted in sedentary and athletic populations when supplementing with magnesium supplementation. It also acts as a muscle relaxer and may improve aerobic performance.
  • Brilla et al. (1992) discovered 26 untrained subjects who participated in a 7 week strength training program in conjunction with magnesium supplementation were able to increase testosterone relative to baseline.

Caffeine Anhydrous:

Caffeine Anhydrous is simply caffeine with no water (around .05%). This has been shown to make caffeine anhydrous more potent because the body will absorb it more readily.

  • Although caffeine can affect a wide variety of motor and mental functions it is most commonly used to improve endurance exercise, focus and cognitive performance, and improve energy levels.
  • Caffeine has also been shown to have a thermogenic effect (heating/calorie burning) at rest and may increase the use of fats for fuel during exercise.
  • According to the research higher doses of caffeine, in the 250-450mg range, are needed to provide an ergogenic benefit.
  • In a study conducted by Astorino et al. (2010), active men given caffeine before resistance training were able to increase maximal torque, power, and volume by 5-8%

Theacrine:

TheaCrine delivers energy shown to last up to 6 hours.

  • Theacrine’s multi-faceted effects come from the synergistic reactions between two neural pathways: dopaminergic and adenosinergic pathways.
  • By affecting these pathways, Theacrine accelerates metabolism, increases energy production, and enables competitive athletes, active individuals and driven professionals to better their physical and mental performance.
  • TheaCrine also helps to maintain inflammation within the normal range, which helps decrease muscle and joint discomfort during and following exercise.

N-phenethyldimethylamine HCL:

Structurally similar to DMAA and believed to create sensations of euphoria while potentially augmenting fat loss.

Higenamine:

Higenamine is a proven beta 1 and 2 adrenergic agonist; meaning that it can help improve focus, enhance mental clarity, increase energy, and burn body fat.

  • Higenamine has also been shown to open up lung capacity by relaxing the trachea, allowing more oxygen to get into your body during training.
  • Higenamine operates as a stimulant that effects some muscle groups in a way to slow contractions down and some to speed them up. During training – longer muscles get a slower contraction rate – which can be good for muscular endurance. The heart will get a faster contraction rate – meaning a faster heart rate.
  • This will work to create a thermogenic effect… as the maximum heart rate required for fat burning is maintained longer.

Cayenne Pepper Extract:

Cayenne has a number of benefits such as helping you burn more fat when you train by targeting fat as an energy source.

  • It can work to keep your blood sugar levels down – thereby blocking excessive fat storage from heightened insulin levels.
  • Moreover, cayenne can boost metabolism and work to act as a mild thermogenic.

Ginger Extract:

Ginger is a spice that can reduce nausea and ease digestion quite effectively.

  • It is commonly used to treat a myriad of stomach problems.  It helps to reduce everything from heartburn to gas and diarrhea.
  • A meta-analysis conducted by Ernst et al. (2000) found ginger was able to reduce nausea induced by seasickness, morning sickness, and chemotherapy induced sickeness.

Yohimbe HCL:

Yohimbe is an alkaloid that is considered a general stimulant that works by increasing adrenaline levels in the body.

  • In some cases Yohimbe increases blood vessel dilation which may enhance energy levels during workouts.
  • Increases in cognitive performance have also been noted in those supplementing with Yohimbe.
  • Yohimbe also may act as a fat burning compound by acting upon the adrenergic receptor system of fat cells, which regulate thermogenesis.
  • A study conducted by Ostojic (2006) found elite male soccer players who supplemented with Yohimbe for 21 days reduced average body fat levels from 9.3% to 7.1%

CapsiAtra:

CapsiAtra™ is a dihydrocapsiate compound naturally found in CH-19 Sweet peppers that holds clinical benefits in weight management, endurance and metabolism.

  • CapsiAtra™ has the ability to increase resting energy expenditure (REE) – allowing the body to burn off more calories than normal, and stimulate thermogenesis – allowing the body to burn calories off of stored fats.
  • It also enhances glycogen sparing, promoting an increase in energy production through the burning off of fat stored within the body instead of carbohydrates.
  • Galgani et al. (2010) discovered subjects who supplemented with Dihydrocapsiate over a one month period were able to increase their resting metabolic rate on a daily basis compared to placebo.

Q: What is the best way to take Helios XT?
A: As a dietary supplement take 1 serving (1 capsule) in the morning or before cardiovascular activity.

Q: Do you recommend combining Helios XT with pre-workouts or other stimulants?
A: Due to the high caffeine/stimulant content found in Helios XT (in order to produce a thermogenic effect) we DO NOT recommend stacking it with your pre-workout or other stimulants.

Q: How is TheaCrine different from caffeine?
A: TheaCrine is molecularly similar to caffeine, but has many unique properties as well. TheaCrine has a longer duration of action, is non-habituating, improves mood and decreases feelings of stress and irritability, and is less likely to disrupt sleep. And while TheaCrine delivers clean energy without habituation, research is underway that shows combining TheaCrine with caffeine can have additive benefits.

Niacin:
1. Elam, M. B., Hunninghake, D. B., Davis, K. B., Garg, R., Johnson, C., Egan, D., … & ADMIT Investigators. (2000). Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: a randomized trial. Jama,284(10), 1263-1270.
2. Goldberg, A., Alagona, P., Capuzzi, D. M., Guyton, J., Morgan, J. M., Rodgers, J., … & Samuel, P. (2000). Multiple-dose efficacy and safety of an extended-release form of niacin in the management of hyperlipidemia. The American journal of cardiology, 85(9), 1100-1105.
3. Guyton, J. R. (2007). Niacin in cardiovascular prevention: mechanisms, efficacy, and safety. Current opinion in lipidology, 18(4), 415-420.

Vitamin B6 (Pyridoxine):
1. Czaja, J., Lebiedzinska, A., Marszall, M., & Szefer, P. (2011). Evaluation for magnesium and vitamin B6 supplementation among Polish elite athletes.Roczniki Państwowego Zakładu Higieny, 62(4).
2. Manore, M. M. (2000). Effect of physical activity on thiamine, riboflavin, and vitamin B-6 requirements. The American journal of clinical nutrition, 72(2), 598s-606s.
3. http://vitaminb6benefits.com/vitamin-b6-benefits

Magnesium:
1. Cinar, V., Polat, Y., Baltaci, A. K., & Mogulkoc, R. (2011). Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion. Biological trace element research, 140(1), 18-23.
2. van der Plas, A. A., Schilder, J. C., Marinus, J., & van Hilten, J. J. (2013). An explanatory study evaluating the muscle relaxant effects of intramuscular magnesium sulphate for dystonia in complex regional pain syndrome. The Journal of Pain, 14(11), 1341-1348.
3. Hatzistavri, L. S., Sarafidis, P. A., Georgianos, P. I., Tziolas, I. M., Aroditis, C. P., Zebekakis, P. E., … & Lasaridis, A. N. (2009). Oral magnesium supplementation reduces ambulatory blood pressure in patients with mild hypertension. American journal of hypertension, 22(10), 1070-1075.
4. Golf, S. W., Bender, S., & Grüttner, J. (1998). On the significance of magnesium in extreme physical stress. Cardiovascular Drugs and Therapy,12(2), 197-202.
5. Carpenter, T. O., DeLucia, M. C., Zhang, J. H., Bejnerowicz, G., Tartamella, L., Dziura, J., … & Cohen, D. (2006). A randomized controlled study of effects of dietary magnesium oxide supplementation on bone mineral content in healthy girls. The Journal of Clinical Endocrinology & Metabolism, 91(12), 4866-4872.
6. Held, K., Antonijevic, I. A., Künzel, H., Uhr, M., Wetter, T. C., Golly, I. C., … & Murck, H. (2002). Oral Mg (2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humans. Pharmacopsychiatry,35(4), 135-143.
7. Brilla, L. R., & Haley, T. F. (1992). Effect of magnesium supplementation on strength training in humans. Journal of the American College of Nutrition,11(3), 326-329.

Caffeine Anhydrous:
1. Harland, B. F. (2000). Caffeine and nutrition. Nutrition, 16(7), 522-526.
2. Goldstein, E. R., Ziegenfuss, T., Kalman, D., Kreider, R., Campbell, B., Wilborn, C., … & Wildman, R. (2010). International society of sports nutrition position stand: caffeine and performance. J Int Soc Sports Nutr, 7(1), 5.
3. Spriet, L. L. (1995). Caffeine and performance. International journal of sport nutrition, 5, S84-S84.
4. Astrup, A., Toubro, S., Cannon, S., Hein, P., Breum, L., & Madsen, J. (1990). Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. The American journal of clinical nutrition, 51(5), 759-767.
5. Hogervorst, E., Bandelow, S., Schmitt, J. A., Jentjens, R., Oliveira, M., Allgrove, J. E., … & Gleeson, M. (2008). Caffeine improves physical and cognitive performance during exhaustive exercise.
6. Woolf, K., Bidwell, W. K., & Carlson, A. G. (2008). The effect of caffeine as an ergogenic aid in anaerobic exercise. International journal of sport nutrition,18(4), 412.
7. Stuart, G. R., Hopkins, W. G., Cook, C., & Cairns, S. P. (2005). Multiple effects of caffeine on simulated high-intensity team-sport performance. Medicine and science in sports and exercise, 37(11), 1998.
8. Beck, T. W., Housh, T. J., Schmidt, R. J., Johnson, G. O., Housh, D. J., Coburn, J. W., & Malek, M. H. (2006). The acute effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities. The Journal of Strength & Conditioning Research, 20(3), 506-510.
9. McLellan, T. M., Kamimori, G. H., Voss, D. M., Tate, C., & Smith, S. J. (2007). Caffeine effects on physical and cognitive performance during sustained operations. Aviation, space, and environmental medicine, 78(9), 871-877.
10. Lieberman, H. R., Tharion, W. J., Shukitt-Hale, B., Speckman, K. L., & Tulley, R. (2002). Effects of caffeine, sleep loss, and stress on cognitive performance and mood during US Navy SEAL training. Psychopharmacology, 164(3), 250-261.
11. Costill, D. L., Dalsky, G. P., & Fink, W. J. (1977). Effects of caffeine ingestion on metabolism and exercise performance. Medicine and science in sports, 10(3), 155-158.
12. Kovacs, E. M., Stegen, J. H., & Brouns, F. (1998). Effect of caffeinated drinks on substrate metabolism, caffeine excretion, and Performance. Journal of Applied physiology, 85(2), 709-715.
13. Acheson, K. J., Zahorska-Markiewicz, B., Pittet, P., Anantharaman, K., & Jéquier, E. (1980). Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. The American journal of clinical nutrition, 33(5), 989-997.
14. Dulloo, A. G., Geissler, C. A., Horton, T., Collins, A., & Miller, D. S. (1989). Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. The American journal of clinical nutrition, 49(1), 44-50.

Theacrine:
1. Habowski, S. M., Sandrock, J. E., Kedia, A. W., & Ziegenfuss, T. N. (2014). The effects of TeacrineTM, a nature-identical purine alkaloid, on subjective measures of cognitive function, psychometric and hemodynamic indices in healthy humans: a randomized, double-blinded crossover pilot trial. Journal of the International Society of Sports Nutrition, 11(1), 1-2.
2. Taylor, L., Mumford, P., Roberts, M., Hayward, S., Mullins, J., Urbina, S., & Wilborn, C. (2016). Safety of TeaCrine®, a non-habituating, naturally-occurring purine alkaloid over eight weeks of continuous use. Journal of the International Society of Sports Nutrition, 13(1), 1-14.
3. Kuhman, D. J., Joyner, K. J., & Bloomer, R. J. (2015). Cognitive Performance and Mood Following Ingestion of a Theacrine-Containing Dietary Supplement, Caffeine, or Placebo by Young Men and Women.Nutrients, 7(11), 9618-9632.

N-phenethyldimethylamine HCL:
1. Sabelli HC, Borison RL, Diamond BI, Havdala HS, Narasimhachari N. Phenylethylamine and brain function. Biochem Pharmacol. 1978
2. Calvert R, Vohra S, Ferguson M, Wiesenfeld P. A beating heart cell model to predict cardiotoxicity: effects of the dietary supplement ingredients higenamine, phenylethylamine, ephedrine and caffeine. Food Chem Toxicol. 2015
3. Greenshaw AJ. Functional interactions of 2-phenylethylamine and of tryptamine with brain catecholamines: implications for psychotherapeutic drug action. Prog Neuropsychopharmacol Biol Psychiatry. 1989
4. Nieforth KA. Psychotomimetic phenethylamines. J Pharm Sci. 1971
5. Heuson E, Storgaard M, Huynh TH, Charmantray F, Gefflaut T, Bunch L. Profiling substrate specificity of two series of phenethylamine analogs at monoamine oxidase A and B. Org Biomol Chem. 2014
6. Boulton AA, Juorio AV, Paterson IA. Phenylethylamine in the CNS: effects of monoamine oxidase inhibiting drugs, deuterium substitution and lesions and its role in the neuromodulation of catecholaminergic neurotransmission. J Neural Transm Suppl. 1990

Higenamine:
1. Bai, G., Yang, Y., Shi, Q., Liu, Z., & Zhang, Q. (2008). Identification of higenamine in Radix Aconiti Lateralis Preparata as a beta2‐adrenergic receptor agonist1. Acta Pharmacologica Sinica, 29(10), 1187-1194.
2. Kam, S. C., Do, J. M., Choi, J. H., Jeon, B. T., Roh, G. S., Chang, K. C., & Hyun, J. S. (2012). The relaxation effect and mechanism of action of higenamine in the rat corpus cavernosum. International journal of impotence research, 24(2), 77-83.
3. Tsukiyama, M., Ueki, T., Yasuda, Y., Kikuchi, H., Akaishi, T., Okumura, H., & Abe, K. (2009). Beta2-adrenoceptor-mediated tracheal relaxation induced by higenamine from Nandina domestica Thunberg. Planta medica, 75(13), 1393-1399.
4. Zhou, S. J., & Du, G. Y. (2003). [Effects of higenamine on the cardio-circulatory system]. Zhongguo Zhong yao za zhi= Zhongguo zhongyao zazhi= China journal of Chinese materia medica, 28(10), 910-913.
5. Kang, Y. J., Lee, Y. S., Lee, G. W., Lee, D. H., Ryu, J. C., Yun-Choi, H. S., & Chang, K. C. (1999). Inhibition of activation of nuclear factor κB is responsible for inhibition of inducible nitric oxide synthase expression by higenamine, an active component of aconite root. Journal of Pharmacology and Experimental Therapeutics, 291(1), 314-320.
6. Pyo, M. K., Lee, D. H., Kim, D. H., Lee, J. H., Moon, J. C., Chang, K. C., & Yun-Choi, H. S. (2008). Enantioselective synthesis of (R)-(+)-and (S)-(−)-higenamine and their analogues with effects on platelet aggregation and experimental animal model of disseminated intravascular coagulation.Bioorganic & medicinal chemistry letters, 18(14), 4110-4114.

Cayenne:
1. Singletary, Keith. (2011). Red Pepper: Overview of Potential Health Benefits. Nutrition Today, 46 (1), 33-47.
2. Govindarajan V, Sathyanarayana M. Capsicum-production, technology, chemistry, and quality. Part V. Impact on physiology, pharmacology, nutrition, and metabolism; structure, pungency, pain, and desensitization sequences. Crit Rev Food Sci Nutr. 1991;29:435Y474.
3. Calixto J, Kassuya C, Andre E, Ferreira J. Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions. Pharmacol Ther. 2005;106:179Y208.
4. Conway S. TRPing the switch on pain: an introduction to the chemistry and biology of capsaicin and TRPV1. Chem Soc Rev. 2008;37:1530Y1545.
5. Barceloux D. Pepper and capsaicin (Capsicum and Piper species). In: Barceloux D, ed: Medicial Toxicology of Natural Substances: Foods, Fungi, Medicinal Herbs, Toxic Plants, and Venomous Animals. Hoboken, NJ: John Wiley and Sons; 2008:71Y76.
6. Cosmetic Ingredients Review Expert Panel. Final Report on the safety assessment of Capsicum annuum extract, Capsicum annuum fruit extract, Capsicum annuum resin, Capsicum annuum fruit powder, Capsicum frutescens fruit, Capsicum frutescens fruit extract, Capsicum frutescens resin, and capsaicin. Int J Toxicol. 2007;26(suppl 1):3Y106.
7. Nakagawa H, Hiura A. Capsaicin, transient receptor potential (TRP) protein subfamilies and the particular relationship between capsaicin receptors and smaller primary sensory neurons. Anat Sci Int. 2006;81:135Y155.
8. Reilly C, Taylor J, Lanza D, Carr B, Crouch D, Yost G. Capsaicinoids cause inflammation and epithelial cell death through activation of vanilloid receptors. Toxicol Sci.
9. Dow J1, Simkhovich BZ, Hale SL, Kay G, Kloner RA. Capsaicin-Induced Cardioprotection. Is Hypothermia or the Salvage Kinase Pathway Involved?
10. Imatake K1, Matsui T, Moriyama M. The effect and mechanism of action of capsaicin on gastric acid output.

Ginger:
1. Ernst, E., & Pittler, M. H. (2000). Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. British journal of anaesthesia, 84(3), 367-371.
2. Chaiyakunapruk, N., Kitikannakorn, N., Nathisuwan, S., Leeprakobboon, K., & Leelasettagool, C. (2006). The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis. American journal of obstetrics and gynecology, 194(1), 95-99.
3. Smith, C., Crowther, C., Willson, K., Hotham, N., & McMillian, V. (2004). A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstetrics & Gynecology, 103(4), 639-645.
4. Black, C. D., Herring, M. P., Hurley, D. J., & O’Connor, P. J. (2010). Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. The Journal of Pain, 11(9), 894-903.
5. Wu, K. L., Rayner, C. K., Chuah, S. K., Changchien, C. S., Lu, S. N., Chiu, Y. C., … & Lee, C. M. (2008). Effects of ginger on gastric emptying and motility in healthy humans. European journal of gastroenterology & hepatology, 20(5), 436-440.
6. Wu, K. L., Rayner, C. K., Chuah, S. K., Changchien, C. S., Lu, S. N., Chiu, Y. C., … & Lee, C. M. (2008). Effects of ginger on gastric emptying and motility in healthy humans. European journal of gastroenterology & hepatology, 20(5), 436-440.

Yohimbe HCL:
1. Ostojic, S. M. (2006). Yohimbine: the effects on body composition and exercise performance in soccer players. Research in Sports Medicine, 14(4), 289-299.
2. Ernst, E., & Pittler, M. H. (1998). Yohimbine for erectile dysfunction: a systematic review and meta-analysis of randomized clinical trials. The Journal of urology, 159(2), 433-436.

CapsiAtra™:
1. Galgani, J. E., & Ravussin, E. (2010). Effect of dihydrocapsiate on resting metabolic rate in humans. The American journal of clinical nutrition, 92(5), 1089-1093.
2. Lee, T. A., Li, Z., Zerlin, A., & Heber, D. (2010). Effects of dihydrocapsiate on adaptive and diet-induced thermogenesis with a high protein very low calorie diet: a randomized control trial. Nutrition & metabolism, 7(1), 1.
3. Galgani, J. E., Ryan, D. H., & Ravussin, E. (2010). Effect of capsinoids on energy metabolism in human subjects. British journal of nutrition, 103(01), 38-42.
4. Inoue, N., Matsunaga, Y., Satoh, H., & Takahashi, M. (2007). Enhanced energy expenditure and fat oxidation in humans with high BMI scores by the ingestion of novel and non-pungent capsaicin analogues (capsinoids). Bioscience, biotechnology, and biochemistry, 71(2), 380-389.