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Hibern8™

• Get to Sleep Faster
• Promotes Deep REM Sleep
• Increases hGH Release
• Reduces Anxiety
• Enhances Recovery
• 30 Servings

$39.99

Product ID: 1722 Category: .

Sleep represents the best time for muscles to grow. It’s one of the reasons bears can grow to over 600 pounds. But bears don’t sleep, they hibernate! That’s exactly what you can expect from DNA Pharma’s Hibern8™ – deep, restful sleep and grizzly-size gains.

• 4-Aminobutanoic Acid has a sedative effect, promoting deep sleep.
• 1-Carboxy, 2-Amino, 3-Pyrobenzol(3,4 diol) enhances hGH release for improved nighttime recovery.
• Valerian Root has been demonstrated to reduce the time required to fall asleep.
• Melatonin serves as a precursor to serotonin, a relaxation neurotransmitter.
• Huperzine boosts sleep efficiency for more recovery even if a full 8 hours cannot be obtained.

Rest represents the third, but often overlooked, pillar of the ultimate physique – the first two being training and diet. Growth hormone levels increase to as much as 10x their daytime resting levels while we’re asleep, and the ingredients in Hibern8™ foster GH release while reducing stress and inducing a deep sleep. Rest deeply and recover quickly with Hibern8™!

4-Aminobutanoic Acid
Also known as GABA, 4-aminobutanoic acid is a “downer” neurotransmitter.
• Promotes feelings of relaxation
• May increase growth hormone
• Increases sleep quality and efficiency

Taurine
Taurine is an amino acid with a collection of beneficial effects.
• Improves endurance, oxygen consumption, and work capacity all while reducing DNA damage from oxidative stress.
• Increases blood flow and triggers angiogenesis – the formation of new blood vessels.
• Taurine is highly concentrated in the testicles, where it supports testosterone production.

L-Tyrosine
L-Tyrosine is a precursor to neurotransmitters, noradrenaline and dopamine, that can improve mood and cognition.
• Acts as an adaptogen, improving resistance to stress and anxiety.
• Enhances mood via increasing dopamine concentrations.

1-Carboxy, 2-Amino, 3-Pyrobenzol(3,4 diol)
1-Carboxy, 2-Amino, 3-Pyrobenzol(3,4 diol) is a direct precursor to dopamine.
• Increases growth hormone release
• Decreases cortisol
• Enhances sexual function in men

Valerian Root Extract
Valerian Root is commonly used as a tea to promote relaxation and sedation.
• Works synergistically with GABA by enhancing GABA signaling
• Reduces anxiety and makes it easier to fall asleep.
• Has been demonstrated to increase sleepiness and drowsiness vs. placebo

Melatonin
Melatonin is a precursor to serotonin. It is used as a non-addictive sleep aid.
• Melatonin helps regulate circadian rhythm and improves sleep quality.
• Increases the spike in nighttime GH release.
• Improves health of the digestive system.

Huperzine A
Huperzine, from huperzia serrata, is an acetylcholinesterase inhibitor, which functions to increase acetylcholine concentrations within the body.
• Helps enhance cholinergic transmission and focus.
• May increase nerve growth factor and aid in neurogenesis.

Q: What is the best way to use Hibern8?
A: As a dietary supplement, take 1 serving (3 capsules) of Hibern8 approximately 30 minutes prior to going to sleep.

Q: Is Hibern8 addictive?
A: No. Hibern8 is non-habit forming and does not form dependence.

Q: Can I take Hibern8 during the day?
A: It is not recommended to take Hibern8 during the day. It is likely to make you drowsy and inattentive due to its sleep enhancing effects.

4-Aminobutanoic Acid
1. Halson, S. L. (2014). Sleep in elite athletes and nutritional interventions to enhance sleep. Sports Medicine, 44(1), 13-23.
2. Meyerhoff, D. J., Mon, A., Metzler, T., & Neylan, T. C. (2014). Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality. Sleep, 37(5), 893-900.
3. Cavagnini, F., Invitti, C., Pinto, M., Maraschini, C., Di Landro, A., Dubini, A., & Marelli, A. (1980). Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta endocrinologica, 93(2), 149-154.
4. Powers, M. E., Yarrow, J. F., Mccoy, S. C., & Borst, S. E. (2008). Growth hormone isoform responses to GABA ingestion at rest and after exercise. Medicine and science in sports and exercise, 40(1), 104-110.

Taurine
1. Zhang, M., Izumi, I., Kagamimori, S., Sokejima, S., Yamagami, T., Liu, Z., & Qi, B. (2004). Role of taurine supplementation to prevent exercise-induced oxidative stress in healthy young men. Amino acids, 26(2), 203-207.
2. BOUCHAMA, A., YUSUF, A., AL-SEDAIRY, S. U. L. T. A. N., & EL-YAZIGI, A. D. N. A. N. (1993). Alteration of taurine homeostasis in acute heatstroke.Critical care medicine, 21(4), 551-554.
3. Gwacham, N., & Wagner, D. R. (2012). Acute effects of a caffeine-taurine energy drink on repeated sprint performance of American college football players. Int J Sport Nutr Exerc Metab, 22(2), 109-116.
4. Warskulat, U., Brookmann, S., Felsner, I., Brenden, H., Grether‐Beck, S., & Häussinger, D. (2008). Ultraviolet A induces transport of compatible organic osmolytes in human dermal fibroblasts. Experimental dermatology, 17(12), 1031-1036.

L-Tyrosine
1. Benedict, C. R., Anderson, G. H., & Sole, M. J. (1983). The influence of oral tyrosine and tryptophan feeding on plasma catecholamines in man. The American journal of clinical nutrition, 38(3), 429-435.
2. Alonso, R., Gibson, C. J., Wurtman, R. J., Agharanya, J. C., & Prieto, L. (1982). Elevation of urinary catecholamines and their metabolites following tyrosine administration in humans. Biological psychiatry, 17(7), 781-790.
3. Agharanya, J. C., Alonso, R., & Wurtman, R. J. (1981). Changes in catecholamine excretion after short-term tyrosine ingestion in normally fed human subjects. The American journal of clinical nutrition, 34(1), 82-87.
4. Acworth, I. N., During, M. J., & Wurtman, R. J. (1988). Tyrosine: effects on catecholamine release. Brain research bulletin, 21(3), 473-477.
5. Neri, D. F., Wiegmann, D., Stanny, R. R., Shappell, S. A., McCardie, A., & McKay, D. L. (1995). The effects of tyrosine on cognitive performance during extended wakefulness. Aviation, space, and environmental medicine.

1-Carboxy, 2-Amino, 3-Pyrobenzol(3,4 diol)
1. HORTTA, H., SATO, Y., ADACHI, H., SUZUKI, N., KATO, R., HISASUE, S., … & TSUKAMOTO, T. (1998). Effects of levodopa on nocturnal penile tumescence: a preliminary study. Journal of andrology, 19(5), 619-624.
2. Müller, T., Welnic, J., & Muhlack, S. (2007). Acute levodopa administration reduces cortisol release in patients with Parkinson’s disease. Journal of neural transmission, 114(3), 347-350.
3. Boden, G., Lundy, L. E., & Owen, O. E. (1972). Influence of levodopa on serum levels of anterior pituitary hormones in man. Neuroendocrinology, 10(5), 309-315.
4. Root, A. W., & Russ, R. D. (1972). Effect of L-dihydroxyphenylalanine upon serum growth hormone concentrations in children and adolescents. The Journal of pediatrics, 81(4), 808-813.

Valerian Root Extract
1. Yuan, C. S., Mehendale, S., Xiao, Y., Aung, H. H., Xie, J. T., & Ang-Lee, M. K. (2004). The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity. Anesthesia & Analgesia, 98(2), 353-358.
2. Pakseresht, S., Boostani, H., & Sayyah, M. (2011). Extract of valerian root (Valeriana officinalis L.) vs. placebo in treatment of obsessive-compulsive disorder: a randomized double-blind study. Journal of Complementary and Integrative Medicine, 8(1).
3. Leathwood, P. D., & Chauffard, F. (1985). Aqueous extract of valerian reduces latency to fall asleep in man. Planta medica, 51(02), 144-148.
4. Miyasaka, L. S., Atallah, Á. N., & Soares, B. (2006). Valerian for anxiety disorders. Cochrane Database of Systematic Reviews, (4).

Melatonin
1. Van Geijlswijk, I. M., Mol, R. H., Egberts, T. C., & Smits, M. G. (2011). Evaluation of sleep, puberty and mental health in children with long-term melatonin treatment for chronic idiopathic childhood sleep onset insomnia. Psychopharmacology, 216(1), 111-120.
2. Alonso‐Vale, M. I. C., Peres, S. B., Vernochet, C., Farmer, S. R., & Lima, F. B. (2009). Adipocyte differentiation is inhibited by melatonin through the regulation of C/EBPβ transcriptional activity. Journal of pineal research, 47(3), 221-227.
3. Wolden-Hanson, T., Mitton, D. R., McCants, R. L., Yellon, S. M., Wilkinson, C. W., Matsumoto, A. M., & Rasmussen, D. D. (2000). Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. Endocrinology, 141(2), 487-497.
4. Forsling, M. L., Wheeler, M. J., & Williams, A. J. (1999). The effect of melatonin administration on pituitary hormone secretion in man. Clinical endocrinology, 51(5), 637-642.
5. Luthringer, R., Muzet, M., Zisapel, N., & Staner, L. (2009). The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia. International clinical psychopharmacology, 24(5), 239-249.
6. Alstadhaug, K. B., Odeh, F., Salvesen, R., & Bekkelund, S. I. (2010). Prophylaxis of migraine with melatonin A randomized controlled trial. Neurology, 75(17), 1527-1532.

Huperzine
1. Vazquez, J., & Baghdoyan, H. A. (2001). Basal forebrain acetylcholine release during REM sleep is significantly greater than during waking. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 280(2), R598-R601.
2. Kametani, H., & Kawamura, H. (1990). Alterations in acetylcholine release in the rat hippocampus during sleep-wakefulness detected by intracerebral dialysis. Life sciences, 47(5), 421-426.
3. Jouvet, M. (1972). The role of monoamines and acetylcholine-containing neurons in the regulation of the sleep-waking cycle. In Neurophysiology and neurochemistry of sleep and wakefulness (pp. 166-307). Springer, Berlin, Heidelberg.
4. Gillin, J. C., Sitaram, N., & Mendelson, W. B. (1982). Acetylcholine, sleep, and depression. Human Neurobiology, 1(3), 211-219.
5. Liang, Y. Q., & Tang, X. C. (2004). Comparative effects of huperzine A, donepezil, and rivastigmine on cortical acetylcholine level and acetylcholinesterase activity in rats. Neuroscience letters, 361(1-3), 56-59.
6. Datta, S., Calvo, J. M., Quattrochi, J. J., & Hobson, J. A. (1991). Long-term enhancement of REM sleep following cholinergic stimulation. Neuroreport, 2(10), 619-622.